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Childhood Obesity
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Obesity news courtesy of Science Daily News

A vaccine targeting aged cells mitigates metabolic disorders in obese mice ... read more
June 30, 2020
Researchers developed a novel vaccine that removes senescent T cells from adipose tissues. They showed that vaccinated obese mice had improved glucose tolerance and insulin resistance without showing severe adverse events. These findings could help develop a novel therapeutic tool.

Common food additive causes adverse health effects in mice ... read more
June 25, 2020
A common food additive, recently banned in France but allowed in the US and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to new research.

Urine test reveals quality of your diet -- and whether it's the best fit for your body ... read more
June 22, 2020
Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'.

Vegetarians tend to be slimmer and less extroverted than meat eaters, study finds ... read more
June 15, 2020
The less animal products someone consumes, the lower his body mass index on average and the less he tends to be extroverted. A connection with depressive moods as other studies had found could not be confirmed.

New approach to turning on the heat in energy-burning fat cells ... read more
June 12, 2020
Researchers have discovered a new set of signals that cells send and receive to prompt one type of fat cell to convert fat into heat. The signaling pathway, discovered in mice, has potential implications for activating this same type of thermogenic fat in humans.

Breastfeeding helps counteracts BMI gain in children at high risk for obesity ... read more
June 11, 2020
For people whose genes put them at risk of becoming obese, exclusive breastfeeding as a baby can help ward off weight gain later in life.

People who eat a late dinner may gain weight ... read more
June 11, 2020
Eating a late dinner may contribute to weight gain and high blood sugar, according to a small study.

Essential components of dietary restriction revealed ... read more
June 9, 2020
Studies have provided a new understanding into the roles two essential amino acids play in metabolic health, which may help scientists in the fight against obesity.

'Fat burning' molecule has implications for treatment of obesity ... read more
June 8, 2020
Scientists have recently identified a small mitochondrial uncoupler, named BAM15, that decreases the body fat mass of mice without affecting food intake and muscle mass or increasing body temperature.

COVID-19 lockdowns worsen childhood obesity, study finds ... read more
June 3, 2020
Lockdowns implemented across the world due to the COVID-19 pandemic have negatively impacted diet, sleep and physical activity among children with obesity, according to new research.

An imbalance of electrons in the liver may be a common risk factor for disease ... read more
May 28, 2020
Researchers have uncovered an unexpected connection between an imbalance of electrons in liver cells and many metabolic problems that increase the risk for conditions such as cardiovascular disease and fatty liver disease.

Adding a blend of spices to a meal may help lower inflammation ... read more
May 21, 2020
Researchers found that adding six grams of spices to a meal high in fat and carbohydrates resulted in lower inflammation markers hours later.

Scientists identify gene linked to thinness that may help resist weight gain ... read more
May 21, 2020
Researchers used a genetic database of more than 47,000 people in Estonia to identify a gene linked to thinness that may play a role in resisting weight gain in metabolically healthy thin people. They show that knocking out this gene results in thinner flies and mice and find that expression of it in the brain may be involved in regulating energy expenditure.

Inspiring stories from women like themselves helped these moms improve their diet ... read more
May 20, 2020
When researchers asked prospective study participants who they would like to see in videos promoting healthy lifestyle behaviors, the answer was unequivocal: They wanted to see themselves -- that is, other mothers living in low-income households who were overweight or obese. The researchers obliged. And the intervention they designed produced the desired results when it came to improving participants' diet.

Obesity not related to how close you live to fast food or gyms ... read more
May 20, 2020
A new study has shown no correlation between obesity and how close you live to fast food restaurants or gyms. Studies from other countries have previously indicated that these factors may be important in adult obesity.

Foolproof new test to track the fats we eat ... read more
May 15, 2020
A team of researchers has developed a reliable and accurate blood test to track individual fat intake, a tool that could guide public health policy on healthy eating.

Repurposed drug helps obese mice lose weight, improve metabolic function ... read more
May 14, 2020
An off-label experiment in mice using disulfiram, which has been used to treat alcohol use disorder for more than 50 years, consistently normalized body weight and reversed metabolic damage in obese middle-aged mice of both sexes.

Coffee linked to lower body fat in women ... read more
May 13, 2020
Women who drink two or three cups of coffee a day have been found to have lower total body and abdominal fat than those who drink less, according to a new study.

How the body makes triglycerides ... read more
May 13, 2020
Researchers discovered the 3D structure and mode of action of DGAT1, the enzyme that synthesizes triglycerides.

Our ability to focus may falter after eating one meal high in saturated fat ... read more
May 12, 2020
Fatty food may feel like a friend during these troubled times, but new research suggests that eating just one meal high in saturated fat can hinder our ability to concentrate -- not great news for people whose diets have gone south while they're working at home during the COVID-19 pandemic.

Revealing links between education and a good diet ... read more
May 7, 2020
Educational status appears to have positive influence on a healthy diet, particularly in low income countries, according to new research examining European nutritional data.

Viruses from feces can help combat obesity and diabetes ... read more
May 4, 2020
Fecal transplants are currently used to treat certain types of antibiotic-resistant diarrhea and has also been attempted to treat e.g. inflammatory bowel disease. A new study suggests that transplanted intestinal contents could also be effective against obesity and type 2 diabetes. By transplanting feces without bacteria obese mice on a high-fat diet significantly decreased weight gain and normalized their glucose tolerance.

Reduced obesity for weighted-vest wearers ... read more
April 30, 2020
Scientists have found a new method of reducing human body weight and fat mass using weighted vests. The new study indicates that there is something comparable to built-in bathroom scales that contributes to keeping our body weight and, by the same token, fat mass constant.

Higher thrombus risk in men with obesity in adolescence ... read more
April 29, 2020
Men with a history of obesity in their late teens are, in adult life are more at risk of a blood clot (thrombus) in a leg or lung, according to a new study. The risk rises successively and is highest in those who were severely obese in adolescence.

Childhood obesity and high blood pressure warn of future heart disease ... read more
April 28, 2020
A large study in adolescents and children, some as young as 3 years of age, shows a link between obesity, high blood pressure, and later damage to blood vessels.

People with brown fat may burn 15% more calories ... read more
April 28, 2020
Short-term cold exposure may help people with brown fat burn 15% more calories than those without, according to a small study.

Traffic officer protein governs speed of sugar/fat conversion pathway ... read more
April 24, 2020
Scientists have identified a protein sensor that restricts how much sugar and fat our cells convert into energy during periods of starvation. It is possible, the scientists say, that the sensor could be fine-tuned to prompt more sugar and fat conversion in people with metabolic conditions.

Brain insulin sensitivity determines body weight and fat distribution ... read more
April 24, 2020
Just where fat is deposited in the body and to what degree a person may benefit from a lifestyle intervention depends on how sensitive the brain is to insulin. If the person's brain responds sensitively to the hormone, a significant amount of weight can be lost and unhealthy visceral fat. People with brain insulin resistance only showed a slight weight loss. These are the results of a long-term study.

An obesity protein discovery may lead to better treatments ... read more
April 23, 2020
By determining the structure of a key receptor in obesity, scientists have unlocked an opportunity for the development of new drugs.

Dietary counselling introduced in infancy leads to better cardiovascular health in adults ... read more
April 23, 2020
Scientists investigated the long-term effects of dietary counseling on cardiovascular health. The individuals, who had participated in the trial between ages 7 months and 20 years, were invited to a follow-up study at the age of 26. The results show that the intervention group who received dietary counseling had lower serum cholesterol level and better insulin sensitivity than those in the control group.

Specialized nerve cells increase the appetite for high-fat foods ... read more
April 22, 2020
Fat activates nociceptin neurons in the hypothalamus of mice.

Link between obesity and sleep loss ... read more
April 22, 2020
Can staying up late make you fat? Researchers found the opposite to be true when they studied sleep in worms: It's not the sleep loss that leads to obesity, but rather that excess weight can cause poor sleep.

Scents regulate fat storage without affecting eating behavior ... read more
April 16, 2020
Researchers discovered that, in the lab worm C. elegans, certain scents dynamically regulate fat mobilization by interacting with specific olfactory neurons through specific receptors.

Obesity is a critical risk factor for type 2 diabetes, regardless of genetics ... read more
April 15, 2020
Obesity increases the risk of developing type 2 diabetes by at least 6 times, regardless of genetic predisposition to the disease.

Researchers describe possible mechanism for link between obesity and breast cancer ... read more
April 13, 2020
It is widely accepted that higher levels of body fat increase the risk of developing breast cancer, as well as other cancers. A new article proposes a unique theory that a protein secreted by fat cells drives the development of breast cancer.

Potential early biomarker to track development of non-alcoholic fatty liver disease ... read more
April 6, 2020
Research has uncovered a biomarker in humans tied to the development of Non-Alcoholic Fatty Liver Disease that might help doctors detect early stages of the disease. The researchers also determined that this biomarker, a protein known as 'neuronal regeneration related protein' (or NREP), plays a significant role in the regulation of a pathway that is currently being reviewed in clinical trials as a treatment option for the disease.

Brown fat can burn energy in an unexpected way ... read more
April 6, 2020
Researchers have discovered an unexpected biological pathway by which brown fat cells can translate energy into heat.

Larger thighs associated with lower risk of heart disease in obesity ... read more
April 4, 2020
A larger thigh circumference may be associated with lower blood pressure and a reduced risk of heart disease in people with obesity, according to a new study. In overweight and obese Chinese men and women, larger thigh circumferences were associated with lower blood pressure. These findings suggest that carrying more weight on the thighs may be a marker of better heart health in Chinese obese and overweight people, who are at a greater risk of heart disease.

COVID-19 pandemic may exacerbate childhood obesity ... read more
April 3, 2020
Public health scientists predict that school closures due to the COVID-19 pandemic will exacerbate the epidemic of childhood obesity in the United States. Researchers expect that COVID-19-related school closures will double out-of-school time this year for many children in the US and will exacerbate risk factors for weight gain associated with summer recess.

Opioid prescriptions linked to obesity ... read more
April 2, 2020
Two new studies shed light on the relationship between obesity and the use of prescription opioids in the United States.

Most diets lead to weight loss and lower blood pressure, but effects largely disappear after a year ... read more
April 1, 2020
Reasonably good evidence suggests that most diets result in similar modest weight loss and improvements in cardiovascular risk factors over a period of six months, compared with a usual diet.

Infants introduced early to solid foods show gut bacteria changes that may portend future health risks ... read more
March 31, 2020
Infants who were started on solid foods at or before three months of age showed changes in the levels of gut bacteria and bacterial byproducts, called short-chain fatty acids, measured in their stool samples, according to a new study.

Poor fitness may impede long-term success in weight loss program ... read more
March 31, 2020
People who are very out of shape when they begin a behavioral weight loss program lose less weight in the long term than those who are more fit, suggests a new study.

Extract from seeds of the Melinjo tree may improve obesity and diabetes ... read more
March 23, 2020
In Southeast Asia, the fruit, flowers, and leaves of Indonesia's 'Melinjo' tree are traditional foods. Researchers who study plants from around the world for useful medicinal properties have found that Melinjo seed extract (MSE) stimulates the production of adiponectin, a beneficial hormone that improves obesity and diabetes. They also discovered that individual genotype differences were responsible for variations in its efficacy.

Removing belly fat before it sticks to you ... read more
March 19, 2020
Researchers are producing in the lab a human protein tasked with removing triglycerides from the blood stream. Unlocking the secrets of human protein APOA 5 gives us a leg up in treating heart disease.

Too much sugar leads to early death, but not due to obesity ... read more
March 19, 2020
Sugar-rich diets have a negative impact on health independent of obesity. Researchers discovered that the shortened survival of fruit flies fed a sugar-rich diet is not the result of their diabetic-like metabolic issues. The findings instead suggest that early death from excess sugar is related to the build-up of a natural waste product, uric acid.

Parental diet affects sperm and health of future offspring ... read more
March 19, 2020
When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team has identified a key player and the molecular events underlying this phenomenon in mice.

Childhood obesity linked to higher risk of anxiety, depression and premature death ... read more
March 18, 2020
Two new studies underscore health risks associated with childhood obesity. Children with obesity have a three times higher risk of mortality in early adulthood compared with children in the general population and are more likely to suffer from anxiety and depression.

Protein controls fat metabolism ... read more
March 17, 2020
A protein in the cell envelope influences the rate of fatty acid uptake in cells. This process also appears to be altered in overweight people.

Evidence clearly favors taxing sugary drinks ... read more
March 13, 2020
New Zealand should follow the UK and more than 30 other countries in introducing a tax on sugary drinks to tackle obesity and reduce deaths from chronic diseases, leading researchers say.

Solving obesity: Could manipulating microbes offer an alternative to weight loss surgery? ... read more
March 13, 2020
Already considered a global epidemic, human obesity continues to be on the rise. According to the Centers for Disease Control, more than 40% of the U.S. population is considered obese. As interest and understanding of the human microbiome increases, researchers are increasingly looking to the gut for answers that can lead to new, more effective diagnostics and therapies.

Newly discovered brain response to obesity drug may inform future treatments ... read more
March 4, 2020
The FDA-approved drug liraglutide has been shown to help obese patients lose weight by suppressing their appetite. However, where and how the drug acts in the brain was not fully understood, until now. A new preclinical study shows how liraglutide crosses the brain's blood barrier to engage with a region of the brainstem known as the nucleus tractus solitarius, which is responsible for balancing food intake and energy expenditure.

Molecule found in oranges could reduce obesity and prevent heart disease and diabetes ... read more
March 3, 2020
Researchers are studying a molecule found in sweet oranges and tangerines called nobiletin, which they have shown to drastically reduce obesity and reverse its negative side-effects. But why it works remains a mystery.

Resolving bitter debate over low-cal sweeteners ... read more
March 3, 2020
A new study showed that people who periodically drank beverages with the low-calorie sweetener sucralose, which is found in low-cal soft drinks, candy, breakfast bars, and other products, did experience problematic metabolic and neural responses -- but only when a carbohydrate in the form of a tasteless sugar was added to the drink. In contrast, people drinking beverages with low-calorie sweeteners alone, or beverages with real sugar, showed no changes in brain or metabolic response to sugars.

Visceral fat delivers signal to the brain that hurts cognition ... read more
March 3, 2020
Excessive weight around our middle gives our brain's resident immune cells heavy exposure to a signal that turns them against us, setting in motion a crescendo of inflammation that damages cognition, scientists say.

When should you eat to manage your weight? Breakfast, not late-night snacks ... read more
February 28, 2020
The balance between weight gain and weight gain loss is predominantly determined by what you eat, how much you eat, and by how much exercise you get. But another important factor is often neglected... it's not just how many calories you eat, but WHEN you eat them that will determine how well you burn those calories.

Eating a vegetarian diet rich in nuts, vegetables, soy linked to lower stroke risk ... read more
February 28, 2020
People who eat a vegetarian diet rich in nuts, vegetables and soy may have a lower risk of stroke than people who eat a diet that includes meat and fish, according to a new study.

How caloric restriction prevents negative effects of aging in cells ... read more
February 27, 2020
A new study provides the most detailed report to date of the cellular effects of a calorie-restricted diet in rats. While the benefits of caloric restriction have long been known, the new results show how this restriction can protect against aging in cellular pathways.

Possible new treatment strategy for fatty liver disease ... read more
February 26, 2020
Researchers have identified a molecular pathway that when silenced could restore the normal function of immune cells in people with fatty liver disease. The findings could lead to new strategies for treating the condition, which is a major health risk for people with obesity.

Sex-specific traits of the immune system explain men's susceptibility to obesity ... read more
February 26, 2020
Researchers have uncovered important differences between the male and female immune system which may explain why men are more susceptible to obesity and metabolism-related associated diseases, such as heart disease, stroke and diabetes. It has long been known that men are more likely than women to develop unhealthy obesity and related metabolic diseases, while women are more prone to certain autoimmune diseases such as arthritis. These findings suggested the male and female immune systems differ, but until now scientists weren't sure how.

 


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